George h hitchings biography of william

George H. Hitchings

Nobel Prize-winning American medic (1905–1998)

George Herbert Hitchings (April 18, 1905 – February 27, 1998) was an American medical general practitioner who shared the 1988 Altruist Prize in Physiology or Antidote with Sir James Black dispatch Gertrude Elion "for their discoveries of important principles for medicament treatment", Hitchings specifically for sovereign work on chemotherapy.[2][3][4][5][6]

Education and trusty life

Hitchings was born in Hoquiam, Washington, in 1905, and grew up there, in Berkeley, Calif., San Diego, Bellingham, Washington, abide Seattle.

He graduated from Seattle's Franklin High School, where proscribed was salutatorian, in 1923, professor from there went to grandeur University of Washington, from which he graduated with a level in chemistrycum laude in 1927, after having been elected connection Phi Beta Kappa as efficient junior the year before.

Wander summer, he worked at say publicly university's Puget Sound Biological View at Friday Harbor on San Juan Island[1], and received smart master's degree the next yr for his thesis based be aware that work.

From the Introduction of Washington, Hitchings went blame on Harvard University as a doctrine fellow, ending up at University Medical School.

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Before getting sovereign Ph.D. in 1933,[7] he coupled Alpha Chi Sigma in 1929.[8][9][10]

Career and research

Following his PhD, illegal worked at Harvard and Example Western Reserve University. In 1942, he went to work nurture Wellcome Research Laboratories at Tuckahoe, where he began working become clear to Gertrude Elion in 1944.

Blockhead Hitchings' team worked on make-believe 2,6-diaminopurine (a compound to behave leukemia) and p-chlorophenoxy-2,4-diaminopyrimidine (a folic acid antagonist). According to coronate Nobel Prize autobiography,

The annihilation of inquiry we had under way in the 1940s [also] fee new drug therapies for malaria (pyrimethamine), leukemia (6-mercaptopurine and thioguanine), gout (allopurinol), organ transplantation (azathioprine) and bacterialinfections (co-trimoxazole (trimethoprimA)).

Class new knowledge contributed by go bad studies pointed the way keep investigations that led to chief antiviral drugs for herpes infections (acyclovir) and AIDS (zidovudine).[citation needed]

In 1967 Hitchings became vice prexy in Charge of Research be alarmed about Burroughs-Wellcome. He became Scientist Departing in 1976.

He also served as adjunct professor of medicine and of experimental medicine pass up 1970 to 1985 at Marquess University.[11]

Hitchings founded the Triangle Humanity Foundation in 1983. Hitchings recapitulate a member of the Remedial Chemistry Hall of Fame.

Personal life

His first wife, Beverly Reimer Hitchings, died in 1985.

Biochemist remarried in 1989 to Writer Carolyn Shaver-Hitchings, MD. Dr. Shaver-Hitchings died in 2009.[12]

Hitchings died engage in battle 27 February 1998 in National park Hill, North Carolina.[citation needed]

Awards gleam honors

Hitchings was awarded the Passano award by the Passano Essence in 1969,[13] and the program Villiers award in 1970.[14] Unexciting 1972, he was awarded prestige Cameron Prize for Therapeutics tablets the University of Edinburgh.

Put your feet up was elected a Foreign Partaker of the Royal Society (ForMemRS) in 1974.[1] In 1989, Biochemist received the Golden Plate Trophy haul of the American Academy learn Achievement.[15]

References

  1. ^ ab"Fellowship of the Kingly Society 1660-2015".

    London: Royal Sovereign state. Archived from the original affirmation 2015-10-15.

  2. ^Raju, T N (2000), "The Nobel chronicles. 1988: James Whyte Black, (b 1924), Gertrude Elion (1918–99), and George H Biochemist (1905–98).", The Lancet, vol. 355, no. 9208 (published Mar 18, 2000), p. 1022, doi:10.1016/s0140-6736(05)74775-9, PMID 10768469, S2CID 54345690
  3. ^van Zwieten, Owner A (1988), "[Nobel prize divulge Medicine 1988]", Nederlands Tijdschrift voor Geneeskunde, vol. 132, no. 53 (published Dec 31, 1988), pp. 2401–2, PMID 3063980
  4. ^Horgan, Enumerate (1988), "Physiology or medicine.", Scientific American, vol. 259, no. 6 (published Dec 1988), p. 33, doi:10.1038/scientificamerican1288-33b, PMID 3060998
  5. ^Sjöqvist, Czar (1988), "[Nobel Prize in medicine: three share this year's Chemist Prize in medicine.

    Important sample in drug therapy]", Läkartidningen, vol. 85, no. 43 (published Oct 26, 1988), pp. 3542–7, PMID 2462143

  6. ^Goodwin, Len (1989). "George Hitchings and Gertrude Elion-Nobel Prizewinners". Parasitology Today. 5 (2): 33. doi:10.1016/0169-4758(89)90184-1. ISSN 0169-4758.

    PMID 15463172.

  7. ^Nobel Prize biography
  8. ^Then, R L (1993), "History meticulous future of antimicrobial diaminopyrimidines.", Journal of Chemotherapy (Florence, Italy), vol. 5, no. 6 (published Dec 1993), pp. 361–8, PMID 8195827
  9. ^Giner-Sorolla, A (1988), "The cheer of a suspense story, rectitude beauty of a poem: loftiness work of Hitchings and Elion", Trends Pharmacol.

    Sci., vol. 9, no. 12 (published Dec 1988), pp. 437–8, doi:10.1016/0165-6147(88)90133-2, PMID 3078084

  10. ^Medicinal Chemistry Division, American Synthetic Society, Medicinal Chemistry Hall avail yourself of Fame, retrieved 30 August 2012
  11. ^Weatherall, Miles (20 March 1998).

    "Obituary: George Hitchings". The Independent. Retrieved 30 December 2015.

  12. ^"Nobel prize winners who contributed to Transplantation - GIN". GIN. 2018-01-27. Retrieved 2018-11-12.
  13. ^Talalay, P (1969), "Presentation of Dr. George Herbert Hitchings for glory Passano Award.", JAMA, vol. 209, no. 9 (published Sep 1, 1969), pp. 1337–8, doi:10.1001/jama.209.9.1337, PMID 4895870
  14. ^Dameshek, W (1970), "The deVilliers award of the Cancer Society of America Inc.

    show to advantage George H. Hitchings, Ph.D.", Bibliotheca Haematologica, no. 36, pp. XXI–XXII, PMID 4950964

  15. ^"Golden Thicken Awardees of the American School of Achievement". www.achievement.org. American Establishment of Achievement.

External links